The ups and downs of Gs- to Gi-protein switching

Characterising C-X-C Chemokine Receptor 4 Dynamics in the Cell Membrane Using Fluorescence Fluctuation Spectroscopy.

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Discovery of uracil-based antagonists and fluorescent ligands of the P2Y2 receptor.

European journal of medicinal chemistry·2026

CXCR4-EGFR heteromers show ligand-dependent changes in conformation and signaling.

Cell chemical biology·2026

Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis.

The Journal of experimental medicine·2026

Cannabinoid CB2 receptor drives trastuzumab resistance and predicts durable anti-HER2 response.

Oncogene·2026

Homozygosity for rare or common hypomorphic IL23R variants confers a predisposition to tuberculosis in humans.

bioRxiv : the preprint server for biology·2026

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights.

British journal of pharmacology·2026

Behind the photographs: Close relations between German pharmacologists and the British Pharmacological Society in the 1930s observed through the diary of Wolfgang Heubner.

British journal of pharmacology·2026

Photodynamic antimicrobial efficacy and mode of action of polypyridyl-based Ru(II) complexes against multidrug-resistant Klebsiella pneumoniae.

British journal of pharmacology·2026

Selective excitatory effects of γ-glutamyl-glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity.

British journal of pharmacology·2026

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer.

British journal of pharmacology·2026

Gut microbiota-derived indole-3-propionic acid attenuates Arsenic trioxide-induced cognitive impairment by inhibiting ubiquitination and degradation of BRD4.

British journal of pharmacology·2026

Robust Fluorescent Eutectogel with Temperature Resilience and Microenvironment-Regulated Emission for Stimuli-Responsivity.

The journal of physical chemistry. B·2026

Tunable A-site crystal-field modulation enables ultra-sensitive, multi-channel lanthanide thermometry in low-phonon halide lattices.

Materials horizons·2026

Colored Transparent Radiative Cooling Glass Based on a Cellulose Nanocrystal Sandwich Structure.

Small (Weinheim an der Bergstrasse, Germany)·2026

Gallic Acid-Crosslinked EmimBr/AA Ionogels Derived from a Polymerizable Deep Eutectic Solvent toward Intelligent Human-Machine Interfaces.

ACS applied materials & interfaces·2026

Atomic-Scale Strain Relaxation via Ar-Bombarded Surface Modification for Enabling Single-Crystalline β-Ga2O3 (010) Heteroepitaxy.

Nano letters·2026

Microfluidic Gratings for X-Ray Phase Contrast Imaging.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

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The ups and downs of Gs- to Gi-protein switching

Related Concept Videos

Characterising C-X-C Chemokine Receptor 4 Dynamics in the Cell Membrane Using Fluorescence Fluctuation Spectroscopy.

Discovery of uracil-based antagonists and fluorescent ligands of the P2Y2 receptor.

CXCR4-EGFR heteromers show ligand-dependent changes in conformation and signaling.

Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis.

Cannabinoid CB2 receptor drives trastuzumab resistance and predicts durable anti-HER2 response.

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Behind the photographs: Close relations between German pharmacologists and the British Pharmacological Society in the 1930s observed through the diary of Wolfgang Heubner.

Photodynamic antimicrobial efficacy and mode of action of polypyridyl-based Ru(II) complexes against multidrug-resistant Klebsiella pneumoniae.

Selective excitatory effects of γ-glutamyl-glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity.

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Gut microbiota-derived indole-3-propionic acid attenuates Arsenic trioxide-induced cognitive impairment by inhibiting ubiquitination and degradation of BRD4.

Robust Fluorescent Eutectogel with Temperature Resilience and Microenvironment-Regulated Emission for Stimuli-Responsivity.

Tunable A-site crystal-field modulation enables ultra-sensitive, multi-channel lanthanide thermometry in low-phonon halide lattices.

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The ups and downs of Gs- to Gi-protein switching

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