[Effect of water-soluble vitamins on the anti-lysozyme activity of enterobacteria]

The influence of vitamins of group B (B1, B6, B12) and vitamin C on the antilysozyme activity (ALA) of pathogenic and opportunistic bacteria (Salmonella, Klebsiella, Escherichia coli) has been determined in a number of in vitro experiments. In E. coli vitamins had different influence on ALA: vitamins B1 and C (at a concentration of 5 mg/ml) increased this activity in E. coli, while vitamins B12 and C (at concentrations of 0.5 and 0.05 mg/ml) decreased it. In Klebsiella vitamins B1, B12 and C (at a concentration of 0.05 mg/ml) decreased ALA, while after the addition of vitamin C at concentrations of 0.5 and 5 mg/ml into the medium ALA increased. In Salmonella vitamins of group B had no influence on ALA, ascorbic acid at a low concentration (0.5 mg/ml) decreased their capacity for inactivating lysozyme. In enterobacteria vitamin B6 produced no changes in ALA.