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Related Experiment Videos

Volatile agents to avoid ventilating asthmatics.

G Baigel1

  • 1Department of Anesthesia and Intensive Care, Royal Cornwall Hospital, Treliske, Truro, United Kingdom.

Anaesthesia and Intensive Care
|April 26, 2003
PubMed
Summary
This summary is machine-generated.

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Subanesthetic doses of inhalational agents can effectively manage acute severe asthma in awake, spontaneously breathing patients. This approach offers an alternative to mechanical ventilation for some critically ill asthma patients.

Area of Science:

  • Anesthesiology
  • Pulmonology
  • Critical Care Medicine

Background:

  • Acute severe asthma presents a significant clinical challenge, often necessitating mechanical ventilation.
  • Patients refractory to maximal medical therapy require advanced interventions.

Purpose of the Study:

  • To describe the management of awake, spontaneously breathing patients with acute severe asthma using a subanesthetic dose of an inhalational agent.
  • To evaluate the efficacy of this alternative treatment strategy.

Main Methods:

  • Case series describing six patients with acute severe asthma.
  • Administration of a subanesthetic dose of an inhalational agent to awake, spontaneously breathing patients.
  • Monitoring of patient response to treatment.

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Main Results:

  • All six patients demonstrated a dramatic initial response to the inhalational agent.
  • Five patients avoided tracheal intubation and mechanical ventilation.
  • One patient required mechanical ventilation after an initial positive response.

Conclusions:

  • Subanesthetic doses of inhalational agents represent a viable management option for select patients with acute severe asthma.
  • This therapeutic approach may help avert tracheal intubation and mechanical ventilation in critically ill asthma patients.