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Updated: Sep 26, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
Published on: August 4, 2018
Variability across the optic nerve head in scanning laser tomography
J C H Tan1, D F Garway-Heath, R A Hitchings
1Moorfields Eye Hospital and Institute of Ophthalmology, London, UK.
Aim:
To characterise measurement variability in scanning laser tomography of the optic nerve head.
Methods:
21 normal and 21 glaucoma subjects underwent same and separate day test-retest Heidelberg retina tomograph imaging by the same and different operators.
Results:
Rim area was most reproducible among parameters. Its variability tended to be highest temporally and increased (p<0.05) with testing involving different operators and visits. Nature of regional variability differed between glaucoma and normal eyes and between standard and 320 micro m reference planes.
Conclusions:
Rim area is reproducible and potentially useful as a marker of progression. Pattern of variability and the influence of different reference planes, disease, operators, and visits should be considered when evaluating progression.

