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Avian Influenza Surveillance with FTA Cards: Field Methods, Biosafety, and Transportation Issues Solved
Published on: August 2, 2011
Large summertime influenza A outbreak among tourists in Alaska and the Yukon Territory
Timothy M Uyeki1, Suzanne B Zane, Ulana R Bodnar
1Influenza Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. tmu0@cdc.gov
Abstract:
We investigated a large summertime outbreak of acute respiratory illness during May-September 1998 in Alaska and the Yukon Territory, Canada. Surveillance for acute respiratory illness (ARI), influenza-like illness (ILI), and pneumonia conducted at 31 hospital, clinic, and cruise ship infirmary sites identified 5361 cases of ARI (including 2864 cases of ILI [53%] and 171 cases of pneumonia [3.2%]) occurring primarily in tourists and tourism workers (from 18 and 37 countries, respectively). Influenza A viruses were isolated from 41 of 210 patients with ILI at 8 of 14 land sites and 8 of 17 cruise ship infirmaries. Twenty-two influenza isolates were antigenically characterized, and all were influenza A/Sydney/05/97-like (H3N2) viruses. No other predominant pathogens were identified. We estimated that >33,000 cases of ARI might have occurred during this protracted outbreak, which was attributed primarily to influenza A/Sydney/05/97-like (H3N2) viruses. Modern travel patterns may facilitate similar outbreaks, indicating the need for increased awareness about influenza by health care providers and travelers and the desirability of year-round influenza surveillance in some regions.
Insights
A large outbreak of acute respiratory illness (ARI) in Alaska and Canada was primarily caused by influenza A (H3N2) viruses. This highlights the need for traveler awareness and year-round influenza surveillance.
Area of Science:
- Epidemiology
- Virology
- Public Health
Background:
- Large outbreaks of acute respiratory illness (ARI) can significantly impact public health, particularly in regions with high tourist traffic.
- Summertime outbreaks of influenza are less common but can occur, posing a challenge for surveillance and control.
Purpose of the Study:
- To investigate a significant summertime outbreak of ARI in Alaska and the Yukon Territory.
- To identify the causative agent and understand the epidemiology of the outbreak.
- To assess the role of modern travel in disease transmission.
Main Methods:
- Conducted surveillance for ARI, influenza-like illness (ILI), and pneumonia across 31 sites (hospitals, clinics, cruise ship infirmaries).
- Isolated and antigenically characterized influenza viruses from affected individuals.
- Estimated total ARI cases based on reported data.
Main Results:
- Identified 5361 cases of ARI, including 2864 ILI and 171 pneumonia cases, predominantly among tourists and tourism workers.
- Isolated influenza A/Sydney/05/97-like (H3N2) viruses from 41 patients with ILI; no other predominant pathogens were found.
- Estimated over 33,000 ARI cases occurred during the outbreak, primarily attributed to influenza A (H3N2).
Conclusions:
- Influenza A (H3N2) was the primary cause of the large summertime ARI outbreak.
- Modern travel patterns can facilitate the rapid spread of influenza across international borders.
- Increased healthcare provider and traveler awareness, along with year-round surveillance in certain regions, is recommended.
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