Apnea-related heart rate variability in congestive heart failure patients

Sleep-disordered breathing (SDB) causes fluctuation of the RR interval. However, the details are uncertain. We studied the characteristics of sleep-related heart rate variation (HRV) in congestive heart failure (CHF) patients with SDB. Ambulatory electrocardiograms and data on respiration (oronasal flow, trachea sound, abdominal wall movement, and oxygen saturation) were simultaneously recorded by a multi-channel digital recorder for 13 CHF patients (8 men and 5 women; mean age, 68 +/- 4 years). Heart rate variation occurred as a result of cyclical apnea attacks between 0.005 and 0.03 Hz (apnea band). The proportion of the apnea band (% apnea) increased with the number of apnea episodes, and SDB was highly likely when the % apnea was > or = 80%. Low-flow oxygen administration effectively reduced apnea frequency, and the apnea-related HRV also decreased. We concluded that apnea-related HRV was useful for detecting and following SDB in CHF cases.