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Survival of children born with congenital anomalies

S Dastgiri1, W H Gilmour, D H Stone

  • 1University of Glasgow, UK.

Archives of Disease in Childhood
|April 30, 2003
PubMed

Insights

Most children born with congenital anomalies survive to age 5. However, survival rates vary significantly by anomaly type, with chromosomal anomalies having the poorest outcomes. This data aids prognosis assessment and healthcare planning.

Area of Science:

  • Pediatric Medicine
  • Medical Genetics
  • Public Health

Background:

  • Congenital anomalies are a significant concern in pediatric health.
  • Understanding long-term survival is crucial for affected families and healthcare providers.

Purpose of the Study:

  • To determine the survival rates of children born with congenital anomalies up to age 5.
  • To identify variations in survival based on specific types of anomalies.

Main Methods:

  • Retrospective analysis of 6153 live-born cases registered with the Glasgow Register of Congenital Anomalies between 1980 and 1997.
  • Follow-up assessment of survival status from birth to 5 years of age.

Main Results:

  • Overall survival to 5 years was 88%.
  • Survival rates varied significantly by anomaly type: chromosomal anomalies (48%) had the lowest survival, while Down's syndrome (84%) and nervous system anomalies (77%) had higher rates.
  • Survival to the first week (94%) and first year (89%) were also reported.

Conclusions:

  • While nearly 90% of infants with congenital anomalies survive to age 5, significant prognostic differences exist among anomaly types.
  • These findings are vital for clinicians, geneticists, and families in assessing prognosis and planning healthcare.
  • The data highlights the need for tailored health care strategies for high-risk populations.
Abstract

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