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HBV associated nephrotic syndrome: resolution with oral lamivudine
F L Connor1, A R Rosenberg, S E Kennedy
1Department of Gastroenterology, Sydney Children's Hospital and University of New South Wales, Randwick, Australia. flconnor@tpgi.com.au
Archives of Disease in Childhood
|April 30, 2003
Abstract:
A 6 year old boy presenting with a five month history of fever, lethargy, and anorexia, was found to have hepatitis B associated membranous glomerulonephropathy and nephrotic syndrome. After two months treatment with oral lamivudine, his proteinuria cleared and serum albumin and aminotransferases normalised, associated with disappearance of hepatitis B e antigen (HBeAg) and appearance of anti-HBeAg antibodies. After 12 months, without side effects, lamivudine was discontinued. He remains well 11 months off treatment.