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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Published on: August 30, 2018

[Pharmacotherapeutic follow-up in hospitalised paediatric patients: adapting Dáder methodology]

D Fontana Raspanti1, N Solá Uthurry

  • 1Departamento de Farmacia. Facultad de Ciencias Químicas. Universidad Nacional de Córdoba. Argentina. danielaf@dqo.fcq.unc.edu.ar

Farmacia Hospitalaria : Organo Oficial De Expresion Cientifica De La Sociedad Espanola De Farmacia Hospitalaria
|April 30, 2003
PubMed

Insights

A new normalized work procedure (NWP) adapted the DA inverted exclamation mark der methodology for pediatric inpatients, identifying and resolving drug-related problems (DRP). The pilot study demonstrated the NWP

Area of Science:

  • Clinical Pharmacy
  • Pediatric Pharmacotherapy
  • Drug-Related Problems (DRP)

Context:

  • The DA inverted exclamation mark der methodology, a framework for identifying and resolving drug-related problems (DRP).
  • Pediatric inpatients present unique challenges in pharmacotherapeutic management.
  • The need for standardized procedures in pediatric pharmacotherapy.

Purpose:

  • To adapt the DA inverted exclamation mark der methodology for pediatric inpatients.
  • To design a normalized work procedure (NWP) for identifying and resolving DRPs in this population.
  • To establish a pilot pharmacotherapeutic follow-up plan to evaluate the NWP.

Summary:

  • A normalized work procedure (NWP) was developed by adapting the DA inverted exclamation mark der methodology for pediatric inpatients.
  • A pilot study involving 21 pediatric inpatients identified 27 DRPs, with 71.4% of patients experiencing at least one DRP.
  • Effectiveness and safety issues constituted the majority of DRPs, with a 55.6% resolution rate.

Impact:

  • The NWP successfully adapted the DA inverted exclamation mark der methodology to a hospital setting for pediatric care.
  • The pilot plan highlighted the critical role of pharmacists in multidisciplinary health teams.
  • Implementation of the NWP can improve the quality of pharmacologic treatments for pediatric inpatients.
Abstract

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