Related Experiment Video
Updated: Aug 17, 2026

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice
Published on: June 15, 2020
[On the connection between left ventricular hypertrophy and diastolic dysfunction in arterial hypertension]
Aim:
To evaluate relationships between arterial pressure (AP), myocardial mass of the left ventricle (LVMM) and left ventricular diastolic function (LVDF) in patients with hypertension stage I and II.
Material And Methods:
89 hypertensive patients and 30 healthy subjects (control group).
Results:
Initial defects in LVDF in the absence of its hypertrophy were detected already in hypertension stage I. At hypertension stage II diastolic dysfunction occurs in marked left ventricular hypertrophy. A close correlation exists between LVMM and LVMM index, on the one hand, and parameters of diastolic dysfunction, on the other hand.
Conclusion:
There is a close correlation between left ventricular hypertrophy and its diastolic dysfunction.
More Related Videos
Related Concept Videos
Pathophysiology of Heart Failure
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Mitral Regurgitation I: Introduction
Mitral Stenosis I: Introduction
Heart Failure II: Pathophysiology
Cardiomyopathy III: Hypertrophic Cardiomyopathy

