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Related Experiment Videos

Cost evaluation of risperidone compared with olanzapine.

Matthew J Byerly1, Mary Weber, Deean Brooks

  • 1Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5959 Harry Hines Boulevard, Professional Office Building 1, Suite 600, Dallas, TX 75390-9101, USA. matt.byerly@utsouthwestern.edu

Psychiatric Services (Washington, D.C.)
|April 30, 2003
PubMed
Summary

This study found that while both risperidone and olanzapine reduced psychiatric hospitalization costs for schizophrenia patients, risperidone was significantly less expensive overall. The median increase in antipsychotic costs was substantially higher for olanzapine treatment.

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Area of Science:

  • Pharmacoeconomics
  • Psychiatry
  • Health Services Research

Background:

  • Schizophrenia treatment involves significant healthcare costs.
  • Antipsychotic medications like risperidone and olanzapine are commonly prescribed.
  • Evaluating cost-effectiveness is crucial for clinical decision-making.

Purpose of the Study:

  • To compare the total treatment costs associated with risperidone versus olanzapine for schizophrenia.
  • To analyze the impact of these antipsychotics on psychiatric hospitalization and medication expenses.

Main Methods:

  • Retrospective analysis of Department of Veterans Affairs data.
  • Inclusion of patients receiving continuous risperidone (N=23) or olanzapine (N=47) treatment.
  • Cost evaluation over nine months pre- and post-treatment initiation.

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Main Results:

  • Both risperidone and olanzapine significantly reduced psychiatric hospitalization costs.
  • Median antipsychotic cost increases were higher with olanzapine ($1,892) than risperidone ($733).
  • Mean dosages: risperidone 3.5 mg/day, olanzapine 18 mg/day.

Conclusions:

  • Risperidone treatment was significantly less expensive than olanzapine for schizophrenia.
  • Both medications demonstrated cost savings in inpatient and outpatient psychiatric care.
  • Cost-effectiveness favors risperidone despite similar reductions in other care costs.