Related Experiment Video
Updated: Sep 26, 2026
Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Research and commentary: Change in exercise tolerance, activity and sleep patterns, and quality of life in patients
Stacey Young-McCaughan1, Mary Z Mays, Sonya M Arzola
1U.S. Army Medical Command in Fort Sam Houston, TX, USA. stacey.young-mccaughan@cen.amedd.army.mil
Purpose/Objectives:
To investigate the feasibility of an exercise program patterned after a phase II cardiac rehabilitation program to improve selected physiologic and psychological parameters of health in patients with cancer.
Design:
Prospective, repeated measures study.
Setting:
Two major military medical centers in the southwestern United States.
Sample:
62 patients diagnosed with cancer within the previous two years. Ages ranged from 24-83 (meanX = 59). Half of the participants were male and half were female. Minorities made up 29% of the sample. Participants had a wide range of cancer diagnoses and all stages of cancer. Fifteen subjects were undergoing treatment when they enrolled in the study. More than half of the subjects exercised prior to their cancer diagnoses, but fewer than half were able to resume an exercise routine following their cancer diagnoses.
Methods:
Subjects met two days each week for 12 weeks for exercise and education.
Main Research Variables:
Exercise tolerance as measured with a graded exercise test, activity and sleep patterns as measured with a wrist actigraph, and quality of life (QOL) as measured with the Cancer Rehabilitation Evaluation System-Short Form.
Findings:
Significant improvements were observed over time in exercise tolerance, selected activity and sleep patterns, and QOL among the 46 (74%) subjects who completed the program.
Conclusions:
Patients with various types and stages of cancer can safely exercise using a cardiac rehabilitation model and can realize significant improvements in exercise tolerance, selected activity and sleep patterns, and QOL.
Implications For Nursing:
Most people are aware that regular exercise is part of a healthy lifestyle. After cancer diagnosis and treatment, patients experience uncertainty regarding how to resume exercise or how to begin an exercise program as part of their rehabilitation. Participation in a structured exercise program can provide patients with a safe environment within which to exercise at an intensity appropriate to their individual needs.
