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Published on: February 10, 2023
Gastrointestinal duplications
P S Puligandla1, L T Nguyen, D St-Vil
1Divisions of Division of Pediatric Surgery and Pathology, The Montreal Children's Hospital, Montreal, Quebec, Canada.
Insights
Prenatal diagnosis of gastrointestinal duplications (GID) significantly reduces complications. Early postnatal investigation and treatment are crucial for asymptomatic infants, preventing life-threatening issues.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Medical Imaging
Background:
- Gastrointestinal duplications (GID) are rare congenital anomalies.
- GID can present with diverse symptoms, including life-threatening complications like volvulus and intussusception.
- The impact of prenatal diagnosis on GID management and outcomes requires further investigation.
Purpose of the Study:
- To review the clinical presentations of gastrointestinal duplications (GID).
- To evaluate the influence of prenatal diagnosis on the treatment and outcomes of GID.
- To identify optimal management strategies for GID.
Main Methods:
- Retrospective review of all GID cases at two pediatric hospitals between 1980 and 2002.
- Analysis of patient demographics, GID location, clinical presentations, and treatment modalities.
- Comparison of outcomes between patients with and without prenatal diagnosis, and across different time periods.
Main Results:
- Seventy-three GID patients were identified, with the ileum and ileocecal valve being the most common locations.
- Neonates and infants commonly presented with vomiting and distension; volvulus occurred in 23.8% of neonates.
- Prenatal diagnosis (n=18) led to a higher proportion of asymptomatic infants (77.2%) and reduced complications compared to the earlier period.
- GID in older children can mimic Crohn's disease, with diagnosis often made during laparotomy.
Conclusions:
- Gastrointestinal duplications (GID) pose significant risks, necessitating prompt management.
- Prenatal diagnosis of GID should prompt early postnatal evaluation and intervention before symptom onset.
- Consideration of laparoscopy/laparotomy is advised for unclear intra-abdominal masses or atypical Crohn's disease presentations.
Background/Purpose:
The aim of this study was to review the presentations of gastrointestinal duplication (GID) and to assess the influence of prenatal diagnosis on treatment.
Methods:
Retrospective review of all GID at 2 pediatric hospitals from 1980-2002 was conducted.
Results:
Seventy-three patients (M43:F30) were identified: 21 neonates, 28 infants (1 to 24 months), 15 children (1 to 10 years), 9 adolescents (>/=11 years). GID location by frequency was ileum (31.5%), ileocaecal valve (30.2%), duodenum (9.6%), stomach (8.2%), jejunum (8.2%), colon (6.8%), and rectum (5.5%). In neonates and infants, vomiting and distension were the most common presentations. Volvulus, caused by a duplication, occurred in 23.8% of neonates and caused the death of one neonate. Intussusception was identified in 10.9% of patients. In older children and adolescents, pain and vomiting were the most common associations. Six of these patients were being treated for Crohn's disease, with the diagnosis of duplication made at laparotomy. Eighteen patients had a prenatal diagnosis by ultrasound scan, with 77.2% of these asymptomatic after birth. Most prenatal diagnoses occurred after 1991 (77.8%). When comparing an earlier period (1980 to 1991; 29 patients) with the current (1992 to 2002; 44 patients), a greater proportion of the latter patients were asymptomatic (36.4 v 13.8%) and had a lower incidence of complications (volvulus/intussusception).
Conclusions:
GID can lead to life-threatening complications. Prenatal diagnosis should lead to expeditious postnatal investigation and treatment before the onset of symptoms or complications. GID in older children can mimic Crohn's disease. Laparoscopy/laparotomy should be considered in patients with atypical Crohn's disease or when the diagnosis of an intraabdominal mass is unclear.
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