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Updated: Sep 26, 2026

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Measuring Single-Cell Mitochondrial DNA Copy Number and Heteroplasmy Using Digital Droplet Polymerase Chain Reaction
Published on: July 12, 2022
[Heteroplasmy in mtDNA in a set of dizygotic twins]
Nadine Kramer1, Frank Heidorn, Günter Weiler
1Institut für Rechtsmedizin am Universitätsklinikum Giessen.
Abstract:
The authors report on a case of a dicygotic female twin pair, one of them containing a T/C heteroplasmy in two (heart and brain) of five analysed organs at position nt204 of the HV2 region. Results and especially the evidence of an unequal distribution of the heteroplasmy are discussed.
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