[Muscular clearance after administration of phenoxybenzamine in shock]

The authors made an experimental investigation in the dog concerning the evolution of the muscular clearance of phenoxybenzamine in the course of de-shocking procedures. The animals were shocked by hemorrhage and were treated by perfusion of volemic mass and administration of phenoxybenzamine. This substance was flowed in paralell with the hemodynamic parameters and the rhythm of the diuresis. It was noted that the direction and the amplitude of changes concerning the half-life of Na131I do not depend on the blood pressure.