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Updated: Aug 11, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
Published on: April 26, 2013
[Molecular construction (superstructures) with adjustable properties based on double-stranded nucleic acids]
Iu M Evdokimov1, V I Salianov, Iu D Nechipurenko
1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia. yevdokim@eimb.ru
Abstract:
Formation of molecular construction that consists of double-stranded molecules of nucleic acids (or synthetic polynucleotides) located at the distance 30-50 A in the spatial structure of particles of their cholesteric liquidcrystalline dispersion and crosslinked by polymeric chelate bridges is described. The resulting superstructure, which possesses peculiar physicochemical properties, could be used as integral biosensor whose properties depend on temperature, the presence of chemical or biologically active compounds of different nature, etc.
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