[Necrotizing external otitis in children in Abidjan (Ivory Coast)]

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Updated: Sep 26, 2026

In Vitro Apical-Out Enteroid Model of Necrotizing Enterocolitis
09:11

In Vitro Apical-Out Enteroid Model of Necrotizing Enterocolitis

Published on: June 8, 2022

E Ette Akre1, A Akre, M J Tanon

  • 1Hôpital Cocody, Service ORL, Abidjan, Côte d'Ivoire.

Revue De Laryngologie - Otologie - Rhinologie
|May 2, 2003
PubMed

Insights

Necrotizing external otitis (NEO) is a severe Pseudomonas infection typically seen in elderly diabetics. This study highlights eight cases in young, undernourished, non-diabetic children, showing good outcomes with local colistin treatment.

Area of Science:

  • Otolaryngology
  • Pediatric Infectious Diseases
  • Microbiology

Background:

  • Necrotizing external otitis (NEO) is a severe Pseudomonas aeruginosa infection of the external auditory canal.
  • NEO predominantly affects elderly patients with diabetes mellitus.
  • Previous reports have documented NEO in non-diabetic individuals.

Observation:

  • Eight cases of NEO in young children (under two years old) were observed.
  • These pediatric patients were characterized by undernourishment and a lack of diabetes.
  • Clinical outcomes were favorable despite limited therapeutic interventions.

Findings:

  • The study identifies a distinct demographic for NEO: young, undernourished, non-diabetic children.
  • Local colistin therapy demonstrated efficacy in treating these cases of NEO.
  • Successful management was achieved even with modest therapeutic approaches.

Implications:

  • These findings expand the known clinical spectrum of necrotizing external otitis.
  • The results suggest that undernourished, non-diabetic children are susceptible to NEO.
  • Local colistin is an effective treatment option for pediatric NEO, offering a valuable therapeutic strategy.

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