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GeneMerge--post-genomic analysis, data mining, and hypothesis testing.

Cristian I Castillo-Davis1, Daniel L Hartl

  • 1Department of Organismic and Evolutionary Biology, Harvard University, Biological Laboratories, 16 Divinity Avenue, Cambridge, MA 02138, USA. ccastillo-davis@oeb.harvard.edu

Bioinformatics (Oxford, England)
|May 2, 2003
PubMed
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GeneMerge is a free web tool that analyzes gene functions and genomic data, providing statistical scores for over-represented categories. This facilitates pathway analysis, population genetics, and comparative genomics research.

Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • GeneMerge is a freely available web-based and standalone program.
  • It is accessible for academic use via the web and for download.

Purpose of the Study:

  • To provide a tool for analyzing functional and genomic data for gene sets.
  • To offer statistical rank scores for identifying over-represented functions or categories.

Main Methods:

  • The program is written in PERL.
  • It analyzes functional or categorical data of various types.

Main Results:

  • GeneMerge returns a range of functional and genomic data.
  • It provides statistical rank scores for over-representation analysis.

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Conclusions:

  • GeneMerge facilitates regulatory and metabolic pathway analysis.
  • It supports population genetic hypotheses testing, cross-experiment comparisons, and chromosomal clustering analysis.
  • The tool enables quick and easy analysis of diverse genomic data for data mining and hypothesis testing.