Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[HLA gene polymorphism and forensic medicine].

Da-qing Jin1, Xiu-fen Zheng

  • 1Chinese People's Public Security University, Beijing 100038. Jdqjdq801@sohu.com

Fa Yi Xue Za Zhi
|May 3, 2003
PubMed
Summary

The Human Leukocyte Antigen (HLA) gene complex is a highly polymorphic genetic system crucial for individual identification. Its advanced research and applications in forensic medicine, including paternity testing, highlight its significance.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Medical and endovascular treatment for acute large vessel occlusion with mild stroke: a real-world nationwide registry.

Journal of neurointerventional surgery·2025
Same author

Predictors of futile recanalization in basilar artery occlusion patients undergoing endovascular treatment: a post hoc analysis of the ATTENTION trial.

Frontiers in neurology·2024
Same author

Neuroprotective mechanism of salvianolic acid B against cerebral ischemia-reperfusion injury in mice through downregulation of TLR4, p-p38MAPK, p-JNK, NF-κB, and IL-1β.

Immunity, inflammation and disease·2023
Same author

Association of baseline core volume and early midline shift in acute stroke patients with a large ischaemic core.

Frontiers in neurology·2023
Same author

Application of Balloon AngioplaSty with the dIstal protection of Stent Retriever (BASIS) technique for acute intracranial artery atherosclerosis-related occlusion.

Frontiers in neurology·2022
Same author

Initial Clinical Experience of Repeat Thrombectomy with a Retrieval Stent (RTRS) with Continuous Proximal Flow Arrest by Balloon Guide Catheter for Acute Intracranial Carotid Occlusion.

Behavioural neurology·2022

Area of Science:

  • Genetics
  • Immunogenetics

Context:

  • The Human Leukocyte Antigen (HLA) gene complex, located on chromosome 6p21, represents the most complex dominant polymorphic genetic system.
  • The HLA system encompasses 108 genotypes, establishing it as a superior human genetic marker.

Purpose:

  • To discuss the research development of HLA polymorphism.
  • To explore the application of HLA polymorphism in forensic medicine.

Summary:

  • The Human Leukocyte Antigen (HLA) gene complex is characterized by extensive polymorphism and is located on chromosome 6p21.
  • With 108 known genotypes, the HLA system serves as a highly effective human genetic marker.
  • This article reviews the advancements in understanding HLA polymorphism and its practical uses in forensic science, particularly in paternity testing and individual identification.

Impact:

  • Provides a comprehensive overview of HLA polymorphism research.
  • Highlights the utility of HLA typing in forensic applications.
  • Establishes HLA as a key genetic marker in forensic investigations.

Related Experiment Videos