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Postpartum posterior leukoencephalopathy syndrome.

R K Garg1

  • 1Department of Neurology, King George's Medical College, Lucknow.

The Journal of the Association of Physicians of India
|May 3, 2003
PubMed
Summary

Posterior leukoencephalopathy syndrome in postpartum women can cause irreversible brain damage, including blindness and seizures. Early recognition and treatment are crucial to prevent permanent neurological deficits.

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Area of Science:

  • Neurology
  • Radiology
  • Obstetrics

Background:

  • Posterior leukoencephalopathy syndrome (PRES) is a neurological condition.
  • PRES can occur in the postpartum period.

Observation:

  • Three postpartum patients presented with PRES.
  • Two patients had persistent posterior parietal and occipital abnormalities, leading to brain atrophy, cortical blindness, and seizures.
  • The third patient's condition was unrecognized for 10 days, with persistent CT abnormalities.

Findings:

  • Delayed recognition and treatment of PRES contributed to permanent brain damage in two patients.
  • Untreated PRES can lead to irreversible neurological damage.

Implications:

  • Emphasizes the importance of prompt diagnosis and management of postpartum PRES.
  • Highlights the potential for severe, long-term neurological sequelae if PRES is missed or delayed.
  • Suggests a need for increased awareness among clinicians regarding PRES in the postpartum setting.

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