Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biochemical engineering: cues from cells.

Subhra Chakrabarti1, Sumana Bhattacharya, Sanjoy K Bhattacharya

  • 1Environmental Biotechnology Division, ABRD Company LLC, 1555 Wood Road, Cleveland, Ohio 44121, USA.

Trends in Biotechnology
|May 3, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lipidomic dataset of optic nerves from the silicone oil-induced ocular hypertension mouse model.

Data in brief·2026
Same author

Phosphatidylserine Decarboxylase Regulates Retinal Ganglion Cell Neurite Outgrowth with Altered Somal Membrane Fluidics and Mitochondrial Morphology.

Biomolecules·2026
Same author

Diabetic Retinopathy as a Risk Factor for Ocular Hypertension or Primary Open Angle Glaucoma in a United States-Based Cohort Study.

Journal of glaucoma·2026
Same author

Phospholipid Interconversion and Transport Are Altered in Glaucoma.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026
Same author

Lipids as pharmacological targets in age-related lens disease.

Trends in pharmacological sciences·2025
Same author

Cerebral vascular tortuosity and aneurysm formation and rupture: a novel vessel tortuosity scale.

Experimental neurology·2025
Same journal

Periphytic biofilms entrap CO<sub>2</sub> from industrial gas mixtures.

Trends in biotechnology·2026
Same journal

CRISPR/Cas14a-based logic system for intelligent microplastic monitoring based on multiple DNA walking mechanisms.

Trends in biotechnology·2026
Same journal

Smart biomaterials: From responsiveness to closed-loop sensing and feedback.

Trends in biotechnology·2026
Same journal

Bacterial spores as a modular platform for the production of amyloids for materials.

Trends in biotechnology·2026
Same journal

The oriGen case and Mexico's regulatory blind spots in genomic biobanking.

Trends in biotechnology·2026
Same journal

A caspase-3-activated protein expression system for apoptosis visualization and apoptosis-pyroptosis conversion to boost antitumor activity.

Trends in biotechnology·2026
See all related articles

Cellular systems exhibit surprising order and integration, enabling them to maintain high productivity despite impure conditions. Understanding this cellular resilience can enhance bioengineering productivity with less pure reagents.

Area of Science:

  • Biotechnology
  • Biochemical Engineering
  • Cellular Biology

Background:

  • Bioengineering systems rely on pure reagents and controlled variables for optimal productivity.
  • Deviations in purity or operational parameters typically cause significant productivity loss in engineered systems.
  • Cellular systems demonstrate a unique ability to function and even enhance productivity under impure conditions.

Purpose of the Study:

  • To explore the inherent order and integration within cellular systems, particularly the cytoplasm.
  • To understand the paradoxical ability of cells to maintain productivity amidst disorder and external signals.
  • To leverage insights from cellular resilience to improve bioengineering practices with impure reagents.

Main Methods:

  • Analysis of cellular cytoplasm as a complex, integrated system.

Related Experiment Videos

  • Investigating the response of cellular systems to external signals under varying purity conditions.
  • Comparative study of engineered bio systems versus natural cellular systems.

    • Main Results:

    • Cellular cytoplasm exhibits a higher degree of order and integration than previously assumed.
    • Cells can adapt to and utilize impure conditions, sometimes increasing productivity.
    • External signals play a crucial role in modulating cellular productivity in non-ideal environments.

    Conclusions:

    • The 'bag of juice' or cytoplasm possesses sophisticated internal organization.
    • Understanding cellular semantics of order and integration is key to enhancing bioengineering.
    • Bioengineers can potentially improve productivity using impure reagents by mimicking cellular strategies.