Related Experiment Video
Updated: Jul 14, 2026

An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome
Published on: September 20, 2022
Control of encrustation and blockage of Foley catheters
D J Stickler1, G L Jones, A D Russell
1Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, Wales, UK. stickler@cardiff.ac.uk <stickler@cardiff.ac.uk>
Abstract:
Urinary catheters often become encrusted and blocked by crystalline Proteus mirabilis biofilms. Results of experiments in a laboratory model of a Foley catheterised bladder infected with P mirabilis showed that when retention balloons were inflated with a solution of triclosan (10 g/L), the catheters drained freely for at least 7 days. Triclosan became impregnated throughout the silicone catheter material and completely inhibited the formation of crystalline biofilm, whereas catheters inflated with water became blocked in 24 h. Our observations suggest a way to control a common complication in patients with long-term indwelling bladder catheters.
More Related Videos
Related Concept Videos
Feedback Inhibition
Allosteric Regulation
Allosteric Regulation
Load-frequency control
Drug Control Governance: Regulatory Bodies and Their Impact
Bioreactor Controls-I

