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Updated: Aug 3, 2026

Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface
Published on: July 21, 2016
Bacterial endocarditis complicating pregnancy: case report and systematic review of the literature
Katie Campuzano1, Henry Roqué, Alan Bolnick
1Division of Maternal-Fetal Medicine, FG-048, Farmington, CT 06030, USA. roque@exchange.uchc.edu
Introduction:
Infectious endocarditis is a rare life-threatening complication of pregnancy. We report a pregnancy complicated by a 3.5-cm infected vegetation of the tricuspid valve initially presenting as unilateral hip pain as well as systematic review of this entity.
Sources:
A MEDLINE review of the English language literature from 1965 to present using the search terms 'endocarditis', 'pregnancy' and 'infection' as well as review of references was performed.
Results:
Sixty-eight cases of infectious endocarditis complicating pregnancy were identified. The calculated maternal and fetal mortality rates were 22.1% and 14.7% respectively.
Conclusions:
With persistent symptomatic lesions, delivery should be considered without regard to measures of fetal lung maturity because of high fetal mortality rates.
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