Common HIV drug-drug interactions

Patients with HIV receive a multitude of medications daily, typically including a triple-drug antiretroviral regimen, prophylactic agents, and therapeutic drugs as needed. While the extensive drug regimens have resulted in improved survival and fewer opportunistic infections, they are also associated with the potential for undesirable and toxic drug interactions. The widespread use of protease inhibitors in particular has greatly increased the number and types of drug interactions that clinicians must monitor.