Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optic pathway tumors in children.

Paul Steinbok1

  • 1Division of Pediatric Neurosurgery, British Columbia's Children's Hospital, and Department of Surgery, University of British Columbia, Canada. psteinbok@cw.bc.ca

Journal of the Chinese Medical Association : JCMA
|May 6, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of Outcomes between Infants above and below 5 Months of Age Undergoing Endoscopic Craniectomy for Sagittal Suture Synostosis.

Pediatric neurosurgery·2025
Same author

The Effect of Selective Dorsal Rhizotomy on Scoliosis in Children With Cerebral Palsy: A Long-term Follow-up Study.

Journal of pediatric orthopedics·2024
Same author

Allometry of human calvaria bones during development from birth to 8 years of age shows a nonlinear growth pattern.

Scientific reports·2024
Same author

Global trends and decision-making in the management of arachnoid cysts.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2023
Same author

Patient-reported outcome measures more than fifteen years after treatment of sagittal or metopic craniosynostosis: a prospective cohort study.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2023
Same author

The Effect of Selective Dorsal Rhizotomy on Hip Displacement in Children With Cerebral Palsy: A Long-term Follow-up Study.

Journal of pediatric orthopedics·2023

Optic pathway tumors are classified into optic nerve, chiasmatic, and chiasmatic/hypothalamic types. Management differs significantly, with observation for chiasmatic tumors and chemotherapy preferred for chiasmatic/hypothalamic tumors.

Area of Science:

  • Neuro-oncology
  • Pediatric neurosurgery
  • Ophthalmology

Background:

  • Optic pathway tumors present diagnostic and management challenges.
  • Classification is crucial, distinguishing between optic nerve, chiasmatic, and chiasmatic/hypothalamic tumors.
  • Optic chiasmatic gliomas management is controversial due to classification issues.

Purpose of the Study:

  • To review the clinical presentation and management of optic pathway tumors.
  • To differentiate between tumor types and guide appropriate therapeutic strategies.
  • To discuss the evolving treatment paradigms for these neoplasms.

Main Methods:

  • Review of existing literature on optic pathway tumors.
  • Classification of tumors based on anatomical location (anterior to chiasm, within chiasm, involving chiasm/hypothalamus).

Related Experiment Videos

  • Analysis of management strategies including observation, surgery, and chemotherapy.

    • Main Results:

    • Optic nerve tumors rarely extend intracranially.
    • Chiasmatic tumors, often associated with NF1, may behave like hamartomas and typically require observation.
    • Chiasmatic/hypothalamic tumors behave as neoplasms, often low-grade astrocytomas, with chemotherapy increasingly favored over radical surgery.

    Conclusions:

    • Accurate tumor classification is essential for effective management of optic pathway tumors.
    • Observation is suitable for benign-behaving chiasmatic tumors.
    • Chemotherapy is the preferred first-line treatment for aggressive chiasmatic/hypothalamic tumors, minimizing surgical morbidity.