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An outbreak of echovirus 13 meningitis in central Israel

E Somekh1, K Cesar, R Handsher

  • 1The Pediatric Infectious Diseases Unit, The Edith Wolfson Medical Center, PO Box 5 Holon 58100, Israel.

Epidemiology and Infection
|May 6, 2003
PubMed

Insights

Echovirus 13 caused a rare aseptic meningitis outbreak in Israel, primarily affecting children under 15. The illness was generally benign, with most patients recovering fully without neurological issues.

Area of Science:

  • * Virology
  • * Epidemiology
  • * Pediatrics

Background:

  • * Echovirus 13 was historically a rare cause of aseptic meningitis.
  • * An unusual outbreak occurred in central Israel during the summer of 2000.

Purpose of the Study:

  • * To investigate the characteristics of an echovirus 13 outbreak.
  • * To identify clinical features and risk factors associated with echovirus 13 meningitis.

Main Methods:

  • * Prospective case-control and retrospective study design.
  • * Viral isolation from cerebrospinal fluid (CSF) specimens.
  • * Analysis of clinical data and patient demographics.

Main Results:

  • * Echovirus 13 was identified in 26 of 58 CSF samples from aseptic meningitis patients.
  • * Patients with echovirus 13 meningitis were predominantly under 15 years old.
  • * Clinical presentation was similar to other enteroviral strains, with higher fever rates and prominent CSF polymorphonuclear (PMN) response.

Conclusions:

  • * Echovirus 13 caused a benign outbreak of aseptic meningitis, mainly in young children.
  • * The outbreak featured elevated white blood cell counts and significant CSF PMN response.
  • * No specific risk factors like daycare or water sources were identified.

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