Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antro-fundic dysfunctions in functional dyspepsia.

Maria Pía Caldarella1, Fernando Azpiroz, Juan-R Malagelada

  • 1Digestive System Research Unit, University Hospital Vall d'Hebron, Autonomous University of Barcelona, Spain.

Gastroenterology
|May 6, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biofeedback Guided by Thoracoabdominal Wall Motion for the Treatment of Rumination: A Randomized Placebo-Controlled Trial.

Gastroenterology·2026
Same author

Automatic colon segmentation on T1-FS MR images.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society·2025
Same author

Laparoendoscopic Rendezvous: An Effective and Safe Approach in the Management of Cholecysto-Choledocholithiasis in Selected Patients.

Journal of clinical medicine·2025
Same author

Hedonic Responses to Meal Ingestion in Patients With Functional Dyspepsia and Postprandial Symptoms.

The American journal of gastroenterology·2024
Same author

Reply.

Gastroenterology·2024
Same author

Thoracoabdominal Wall Motion-Guided Biofeedback Treatment of Abdominal Distention: A Randomized Placebo-Controlled Trial.

Gastroenterology·2024

Functional dyspepsia involves stomach hypersensitivity and impaired fundic relaxation. Antral and fundic dysfunctions interact, potentially overloading a sensitive antrum, contributing to symptoms.

Area of Science:

  • Gastroenterology
  • Physiology

Background:

  • Functional dyspepsia (FD) symptoms are linked to impaired proximal stomach accommodation and hypersensitivity.
  • Investigating antral dysfunctions offers a more comprehensive understanding of FD pathophysiology.

Purpose of the Study:

  • To identify and characterize antral dysfunctions in functional dyspepsia.
  • To explore the interaction between antral and fundic stomach dysfunctions in FD.

Main Methods:

  • Two studies were conducted on 30 FD patients and 22 healthy controls.
  • Selective distention of proximal and distal stomach using air/water bags and tensostat to measure perception, compliance, and fundic relaxation responses to antral distention and nutrient infusion.

Main Results:

Related Experiment Videos

  • FD patients exhibited hypersensitivity in both the proximal stomach and antrum compared to controls.
  • Impaired reflex fundic relaxation was observed in FD patients in response to both antral distention and intestinal nutrient infusion.

    • Conclusions:

    • Antral and fundic dysfunctions are interconnected in causing functional dyspepsia symptoms.
    • Impaired control of fundic accommodation may lead to the overload of a hypersensitive antrum in FD patients.