Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Liver transplantation.

Kathryn L Nash1, Alexander E S Gimson

  • 1Hepatobiliary and Liver Transplant Unit, Addenbrooke's Hospital, Cambridge CB2 2QQ.

Hospital Medicine (London, England : 1998)
|May 7, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Liver transplantation in adults with liver disease due to common variable immunodeficiency leads to early recurrent disease and poor outcome.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·2017
Same author

A comparison of MR elastography and 31P MR spectroscopy with histological staging of liver fibrosis.

European radiology·2012
Same author

Antibiotic prophylaxis in variceal hemorrhage: timing, effectiveness and Clostridium difficile rates.

World journal of gastroenterology·2010
Same author

Hepatocellular carcinoma in patients with chronic hepatitis C virus infection without cirrhosis.

World journal of gastroenterology·2010
Same author

Telaprevir: a new hope in the treatment of chronic hepatitis C?

Advances in therapy·2010
Same author

A massive haematemesis.

BMJ (Clinical research ed.)·2010

Liver transplantation is now a standard therapy for end-stage liver disease. Key challenges include organ availability, managing immunosuppression side effects, and preventing disease recurrence after transplant.

Area of Science:

  • Hepatology and Transplant Surgery
  • Immunology
  • Organ Transplantation

Background:

  • Liver transplantation has transitioned from an experimental approach to a well-established treatment for end-stage liver disease.
  • Despite advancements, significant hurdles remain in liver transplant procedures.
  • These challenges impact patient outcomes and the broader application of this therapy.

Purpose of the Study:

  • To outline the current landscape of liver transplantation.
  • To identify and discuss the primary obstacles in the field.
  • To highlight areas for future research and clinical improvement.

Main Methods:

  • Literature review of recent advancements in liver transplantation.
  • Analysis of current challenges in donor organ procurement.

Related Experiment Videos

  • Review of long-term outcomes and complications associated with immunosuppressive regimens.
  • Examination of strategies for preventing and managing disease recurrence post-transplant.

    • Main Results:

    • Donor organ shortage remains a critical limiting factor for liver transplantation.
    • Long-term complications, including those from immunosuppressive therapy, pose significant risks to recipients.
    • Disease recurrence is a persistent issue affecting graft survival and patient prognosis.

    Conclusions:

    • Liver transplantation is a vital therapy, but its effectiveness is constrained by organ scarcity.
    • Addressing immunosuppression-related complications and disease recurrence is essential for improving long-term transplant success.
    • Further innovation is needed to overcome these persistent challenges in liver transplantation.