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[Study on the regulative effect of isomaltooligosaccharides on human intestinal flora]
Qing Gu1, Yi Yang, Guohong Jiang
1Tianjin Centers for Disease Control and Provention, Tianjin 300011, China.
Objective:
In order to study the effect of Isomaltooligosaccharides on Human and mouse intestinal flora in vivo.
Methods:
1. 30 health subjects (15 male, 15 female) were randomly selected from the clinic of Tianjin CDC. They were provide 15 g Isomaltooligosaccharides once a day for 7 days; 2. 40 BABL/c mice were divided into 4 groups, 3 experimental groups and 1 control group. These 3 experimental groups were fed different dose of Isomaltooligosaccharides by gavage for 7 days. Feces of both human and mice were determined before and at the end of the experiment.
Results:
The results showed that the reproduction of Bifidobacteria and Lactobacillus greatly increased, and the growth of Clostridium perfriengenes was significantly inhibited both in mice and human intestinal tracts.
Conclusion:
Isomaltooligosaccharides could regulate and improve the intestinal flora in both mice and human intestine.