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Obstructive congenital gingival granular cell tumor
Jean-Baptiste Charrier1, Pierre Droullé, Jean-Michel Vignaud
1Department of Maxillofacial Surgery, Centre Hospitalier Régional Universitaire de Nancy, France. jean-baptiste.charrier@college-de-france.fr
Summary
Congenital gingival granular cell tumors are rare, benign oral masses in newborns. This case highlights a large tumor causing airway obstruction, successfully treated with surgery.
Area of Science:
- Oral Pathology
- Pediatric Oncology
- Developmental Biology
Background:
- Congenital gingival granular cell tumors (CGGC) are rare, benign intraoral neoplasms.
- Also known as congenital epulis or Neumann's tumor, they originate from the alveolar ridge.
Observation:
- A large, obstructive CGGC of the mandibular ridge was detected prenatally via ultrasound.
- The tumor presented as a mass protruding from the newborn's mouth, causing airway obstruction.
Findings:
- Complete surgical excision was performed with a successful postoperative recovery.
- Histologic and immunohistochemical analyses, including S-100 protein staining, confirmed the diagnosis.
Implications:
- This case underscores the importance of prenatal diagnosis for obstructive neonatal masses.
- Effective surgical management of CGGC ensures favorable outcomes for affected infants.