Congenital quadricuspid aortic valve: report of nine surgical cases

Goichi Yotsumoto1, Yoshifumi Iguro, Tamahiro Kinjo

  • 1Second Department of Surgery, Kagoshima University, Faculty of Medicine, Sakuragaoka, Kagoshima, Japan.

Insights

Congenital quadricuspid aortic valves are rare, often causing aortic regurgitation and requiring aortic valve replacement (AVR). This study details their characteristics and surgical outcomes.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Pathology

Background:

  • Congenital quadricuspid aortic valve is a rare cardiac anomaly.
  • It frequently leads to significant aortic valve dysfunction, primarily aortic regurgitation.
  • Understanding its clinicopathologic features is crucial for surgical management.

Purpose of the Study:

  • To describe the clinicopathologic characteristics of congenital quadricuspid aortic valves requiring surgical intervention.
  • To analyze the surgical outcomes of patients with this condition.

Main Methods:

  • Retrospective review of 616 aortic valve operations over 20 years.
  • Identification and analysis of nine patients with congenital quadricuspid aortic valves.
  • Macroscopic, histological, and classification (Hurwitz and Roberts) assessment of the valves.

Main Results:

  • Nine patients (1.46%) with quadricuspid aortic valves were identified, with a mean age of 60.
  • Eight patients presented with aortic regurgitation, one with aortic stenosis and mild regurgitation.
  • Histological findings included fibrous thickening and myxoid degeneration; calcification and fenestration were also observed.

Conclusions:

  • Congenital quadricuspid aortic valve is an uncommon cause of aortic valve disease.
  • Aortic valve replacement (AVR) is an effective surgical treatment for this condition.
  • Further research into valve repair strategies may be warranted.

Related Concept Videos

Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.