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Published on: December 11, 2017
Congenital quadricuspid aortic valve: report of nine surgical cases
Goichi Yotsumoto1, Yoshifumi Iguro, Tamahiro Kinjo
1Second Department of Surgery, Kagoshima University, Faculty of Medicine, Sakuragaoka, Kagoshima, Japan.
Insights
Congenital quadricuspid aortic valves are rare, often causing aortic regurgitation and requiring aortic valve replacement (AVR). This study details their characteristics and surgical outcomes.
Area of Science:
- Cardiology
- Cardiac Surgery
- Pathology
Background:
- Congenital quadricuspid aortic valve is a rare cardiac anomaly.
- It frequently leads to significant aortic valve dysfunction, primarily aortic regurgitation.
- Understanding its clinicopathologic features is crucial for surgical management.
Purpose of the Study:
- To describe the clinicopathologic characteristics of congenital quadricuspid aortic valves requiring surgical intervention.
- To analyze the surgical outcomes of patients with this condition.
Main Methods:
- Retrospective review of 616 aortic valve operations over 20 years.
- Identification and analysis of nine patients with congenital quadricuspid aortic valves.
- Macroscopic, histological, and classification (Hurwitz and Roberts) assessment of the valves.
Main Results:
- Nine patients (1.46%) with quadricuspid aortic valves were identified, with a mean age of 60.
- Eight patients presented with aortic regurgitation, one with aortic stenosis and mild regurgitation.
- Histological findings included fibrous thickening and myxoid degeneration; calcification and fenestration were also observed.
Conclusions:
- Congenital quadricuspid aortic valve is an uncommon cause of aortic valve disease.
- Aortic valve replacement (AVR) is an effective surgical treatment for this condition.
- Further research into valve repair strategies may be warranted.
Abstract:
We report the clinicopathologic characteristics of the congenital quadricuspid aortic valve necessitating surgery. Among 616 patients for whom we performed an aortic valve operation over the past 20 years, nine patients (1.46%) (five men and four women, mean age 60 years) with quadricuspid aortic valve were encountered. All had aortic regurgitation (AR) except one with aortic stenosis and mild regurgitation (ASr). All were free of cardiac anomaly including that of the coronary arterial system. Macroscopically, severe calcification of the valve was seen in the one case of ASr. Fenestration of the cusp was seen in five cases of AR. Infective endocarditis was not seen. Histological study disclosed fibrous thickening and myxoid degeneration in the AR cases. In accordance with the Hurwitz and Roberts classification, four valves were type b (three equal-sized cusps and one smaller cusp), two valves were type a (four equal-sized cusps), two valves were type d (one large, two intermediate, and one small cusp), and one valve was type g (four unequal-sized cusps). Valve repair failed in one patient and was converted to valve replacement during the operation. All patients underwent successful aortic valve replacement (AVR).
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