New insights into ciliary function: kidney cysts and photoreceptors

Aldehyde dehydrogenase 1 A1 regulates the transcription of PD-L1 and its targeting with disulfiram together with PD-L1 immunotherapy synergistically delays cyst growth in ADPKD.

Kidney international·2025

In vivo base editing rescues ADPKD in a humanized mouse model.

Nature communications·2025

Cellular senescence and its association with aldose reductase promote cyst growth in autosomal dominant polycystic kidney disease.

Kidney international·2025

SMYD3 Controls Ciliogenesis by Regulating Distinct Centrosomal Proteins and Intraflagellar Transport Trafficking.

International journal of molecular sciences·2024

DNA methyltransferase 1 (DNMT1) promotes cyst growth and epigenetic age acceleration in autosomal dominant polycystic kidney disease.

Kidney international·2024

Overexpression of SMYD3 Promotes Autosomal Dominant Polycystic Kidney Disease by Mediating Cell Proliferation and Genome Instability.

Biomedicines·2024

The effectiveness of green place-based industrial policy: Evidence from the Inflation Reduction Act.

Proceedings of the National Academy of Sciences of the United States of America·2026

Overcoming the blood-brain barrier using central nervous system-accessing lipid nanoparticles for enhanced mRNA therapeutics.

Proceedings of the National Academy of Sciences of the United States of America·2026

Distinct transcriptional logics of catechol siderophore transporters in Pseudomonas aeruginosa for efficient iron acquisition.

Proceedings of the National Academy of Sciences of the United States of America·2026

Emergence of biosignatures on Earth and implications for life detection.

Proceedings of the National Academy of Sciences of the United States of America·2026

Mechanistic insights into cooperative permeation of glycerol and water through human aquaporin-10.

Proceedings of the National Academy of Sciences of the United States of America·2026

Beyond "non-significant" results: Why and how to test for practical equivalence.

Proceedings of the National Academy of Sciences of the United States of America·2026

Reactivation of Choroidal Neovascularization in Bilateral Punctate Inner Choroidopathy: A Case Report.

Cureus·2026

Incidence and Recovery of 15-Letter Loss of Visual Acuity in Patients With Neovascular Age-Related Macular Degeneration on Antivascular Endothelial Growth Factor Therapy.

Journal of vitreoretinal diseases·2026

Severe visual impairment as a complication of autism spectrum disorder.

Documenta ophthalmologica. Advances in ophthalmology·2026

Aqueous Humor Proteomics Reveals the Molecular Basis for Differential Treatment Responses in nAMD and pmCNV.

Investigative ophthalmology & visual science·2026

High-Resolution OCT of Retinal Vessels in Eyes with Vascular Leakage.

Ophthalmology science·2026

Dynamic changes in aqueous humor cytokines and OCTA parameters during aflibercept loading in treatment-naive neovascular age-related macular degeneration.

Frontiers in medicine·2026

Related Experiment Videos

New insights into ciliary function: kidney cysts and photoreceptors

Related Concept Videos

Aldehyde dehydrogenase 1 A1 regulates the transcription of PD-L1 and its targeting with disulfiram together with PD-L1 immunotherapy synergistically delays cyst growth in ADPKD.

In vivo base editing rescues ADPKD in a humanized mouse model.

Cellular senescence and its association with aldose reductase promote cyst growth in autosomal dominant polycystic kidney disease.

SMYD3 Controls Ciliogenesis by Regulating Distinct Centrosomal Proteins and Intraflagellar Transport Trafficking.

DNA methyltransferase 1 (DNMT1) promotes cyst growth and epigenetic age acceleration in autosomal dominant polycystic kidney disease.

Overexpression of SMYD3 Promotes Autosomal Dominant Polycystic Kidney Disease by Mediating Cell Proliferation and Genome Instability.

The effectiveness of green place-based industrial policy: Evidence from the Inflation Reduction Act.

Overcoming the blood-brain barrier using central nervous system-accessing lipid nanoparticles for enhanced mRNA therapeutics.

Distinct transcriptional logics of catechol siderophore transporters in Pseudomonas aeruginosa for efficient iron acquisition.

Emergence of biosignatures on Earth and implications for life detection.

Mechanistic insights into cooperative permeation of glycerol and water through human aquaporin-10.

Beyond "non-significant" results: Why and how to test for practical equivalence.

Reactivation of Choroidal Neovascularization in Bilateral Punctate Inner Choroidopathy: A Case Report.

Incidence and Recovery of 15-Letter Loss of Visual Acuity in Patients With Neovascular Age-Related Macular Degeneration on Antivascular Endothelial Growth Factor Therapy.

Severe visual impairment as a complication of autism spectrum disorder.

Aqueous Humor Proteomics Reveals the Molecular Basis for Differential Treatment Responses in nAMD and pmCNV.

High-Resolution OCT of Retinal Vessels in Eyes with Vascular Leakage.

Dynamic changes in aqueous humor cytokines and OCTA parameters during aflibercept loading in treatment-naive neovascular age-related macular degeneration.

Related Experiment Videos

New insights into ciliary function: kidney cysts and photoreceptors

Related Concept Videos

Related Articles