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Updated: Aug 10, 2026

Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice
Published on: March 10, 2015
[Clinical efficacy of using ximedon in surgical practice]
S G Izmaĭlov1, G A Izmaĭlov, I V Zaikonnikova
1Military Medical Institute, Kazan State Medical University, Respublican Clinical Hospitals No. 1, No. 5, No. 7, Septic Center, Kazan.
Abstract:
Results of clinical trial of the new pyrimidine derivative--ximedone are presented. The drug was administered per os 0.5 g x 4 times a day (0.5 h before meals). Total course dose achieved 60 g. Ximedone implementation for complex treatment of burns, trophic ulcer of lower limbs, different inflammations demonstrated positive results. Prophylaxy administration of the drug in abdominal surgery at acute appendix resulted with lower incidence of postoperative complications. High efficacy and good tolerability of the drug allows to recommend it for wide medical use.
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