Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Thin-layer cytology in urinary diagnosis].

A Caldarella1, A M Buccoliero, G L Taddei

  • 1Dipartimento di Patologia Umana e Oncologia, Università degli Studi di Firenze, Viale Gian Battista Morgagni 85, 50134 Firenze. adele.caldarella@unifi.it

Pathologica
|May 9, 2003
PubMed
Summary

The thin-layer method in urinary cytology improves cell recovery and preservation, offering better diagnostic accuracy. This technique enhances the detection of low-grade transitional cell carcinomas often missed by other methods.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Congenital cranial fasciitis of the ethmoid bone with extensive intracranial and facial involvement: a case report and review of the literature.

International journal of oral and maxillofacial surgery·2025
Same author

Cardiac valve hemangioma in two cases of sudden infant death.

La Clinica terapeutica·2025
Same author

Patients with cancer who will be cured and projections of complete prevalence in Italy from 2018 to 2030.

ESMO open·2024
Same author

Myxoid glioneuronal tumor: Histopathologic, neuroradiologic, and molecular features in a single center series.

Neoplasia (New York, N.Y.)·2023
Same author

Postmortem diagnosis of 21-hydroxylase deficiency congenital adrenal hyperplasia: medico-legal issues.

Journal of biological regulators and homeostatic agents·2019
Same author

The burden of cutaneous adnexal carcinomas and the risk of associated squamous cell carcinoma: a population-based study.

The British journal of dermatology·2018

Area of Science:

  • Uropathology
  • Cytopathology
  • Diagnostic cytology

Background:

  • Urinary cytology is crucial for detecting bladder cancer.
  • Traditional methods like cytospin and filter smears have limitations in cell recovery and artifact reduction.
  • Improving diagnostic yield in urinary cytology remains an ongoing challenge.

Purpose of the Study:

  • To evaluate the efficacy of the thin-layer method in urinary cytology.
  • To compare the thin-layer method with cytospin smears and filter preparations.
  • To assess improvements in cellularity, morphology, and background quality.

Main Methods:

  • Comparative study of three urinary cytology preparation methods: cytospin, filter, and thin-layer.
  • Evaluation of cellularity, cellular morphology, and background characteristics.

Related Experiment Videos

  • Assessment of cytohistologic correlations.

    • Main Results:

    • The thin-layer method demonstrated superior cell recovery and preservation compared to cytospin and filter methods.
    • Reduced background artifact was observed with the thin-layer technique.
    • Enhanced cytohistologic correlation was achieved with the thin-layer method.

    Conclusions:

    • The thin-layer method significantly improves cell recovery, preservation, and reduces background artifacts in urinary cytology.
    • This technique offers higher diagnostic accuracy and better cytohistologic correlation.
    • Thin-layer preparation increases the detection rate of low-grade transitional cell carcinomas, improving diagnostic sensitivity.