Hypertension and nephritic urine sediment following retroperitoneal lymph node dissection
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Updated: Sep 26, 2026

Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
Ryand F. Paterson1, Larry Goldenberg, Barry O. Kassen
1Department of Surgery, Division of Urology, University of British Columbia, Vancouver, BC.
Abstract:
Retroperitonela lymph node dissection (RPLND), cisplatin-based chemotherapy, and tumor surveillance has dramatically improved survival of patients with non-seminomatous germ cell tumors. Complications, including renal vascular injuries, have been encountered with post-chemotherapy RPLND. We report on a patient with delayed renovascular hypertension and nephritic sediment following RPLND. A thirty year old man presented with well-controlled hypertension following treatment of a left testicular non-seminomatous germ cell tumor 11 years earlier. Post-orchiectomy investigation revealed retroperitoneal lymphadenopathy which was treated with cispaltin-based chemotherapy. A residual mass was managed surgically and during perihilar dissection, the left renal vein was injured and repaired. Current investigation revealed hypertension and a nephritic urine sediment, both of which resolved with left simple nephrectomy. We believe that inadvertent renal artery injury was responsible for this late complication.
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