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Effect of bilateral stimulation of the subthalamic nucleus on parkinsonian dysarthria
Michèle Gentil1, Serge Pinto, Pierre Pollak
1Inserm, Unit 318, CHU, Service Neurologie, BP 217 38043, Grenoble cedex 9, France. mj.gentile@wanadoo.fr
Abstract:
Never was the effect of bilateral stimulation of the subthalamic nucleus (STN) evaluated quantitatively on all the components of speech production, that is articulation, respiration and phonation, at the same time. It is the purpose of this study which uses force measurements of the articulatory organs and acoustic analysis in 16 parkinsonian patients. With STN stimulation, reaction and movement time of the articulatory organs decreased and their maximal strength, as well as their precision increased. We also noted a large beneficial effect on voice with a significant improvement in respiratory and phonatory functions.
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