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Related Experiment Videos

Autogenous fat injection for vocal fold atrophy.

Ming-Wang Hsiung1, Yaoh-Shiang Lin, Wan-Fu Su

  • 1Department of Otolaryngology, Tri-Service General Hospital, National Defense Medical Center, No 325, Chenggung Road, Section 2, 114 Taipei, Taiwan ROC. hsiunm01kimo@yahoo.com.tw

European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
|May 9, 2003
PubMed
Summary

Autogenous fat injection effectively treats vocal fold atrophy with complete glottal closure (VFACGC), improving voice quality and function. This procedure also resolved muscular tension dysphonia in over half of the patients studied.

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Area of Science:

  • Otolaryngology
  • Regenerative Medicine

Background:

  • Autogenous fat augmentation is a known treatment for glottic insufficiency.
  • Limited data exists on its efficacy for vocal fold atrophy with complete glottal closure (VFACGC).

Observation:

  • This retrospective study evaluated 21 patients with VFACGC undergoing fat injection.
  • 13 patients had pre- and post-procedure assessments of perceptual, acoustic, phonatory, and videolaryngostroboscopic functions.
  • Mean follow-up was 9.5 months.

Findings:

  • Excellent results were observed in 15 patients; four experienced failure.
  • Significant improvements were noted in perceptual voice ratings (grade, roughness, breathiness) and videolaryngostroboscopic parameters (vocal fold edge linearity, vibration amplitude, mucosal wave).

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  • 54% of patients with co-existing muscular tension dysphonia (MTD) experienced MTD resolution post-procedure.

    • Implications:

    • Fat injection is an effective autogenous implant for VFACGC, often misdiagnosed as MTD.
    • It offers significant functional voice improvement and can resolve associated MTD.
    • Repeat procedures may mitigate fat re-absorption issues.