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Updated: Jul 21, 2026

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
Published on: March 30, 2014
Antiretroviral therapy in the treatment-experienced patient
1Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Abstract:
Despite the growing number of new antiretroviral agents, planning therapy for treatment-experienced patients remains extremely challenging. Cross-resistance within the three currently available classes of drugs limits the number of sequential drug regimens that can be expected to suppress viral replication effectively. An understanding of resistance and cross-resistance, together with judicious use of resistance testing, can help clinicians design better treatment regimens for patients experiencing virologic failure while taking antiretroviral therapy.
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