Related Experiment Videos
Efficient and regioselective synthesis of 2-alkyl-2H-indazoles
Mui Cheung1, Amogh Boloor, Jeffrey A Stafford
1GlaxoSmithKline, Five Moore Drive, Research Triangle Park, North Carolina 27709, USA. mc72785@gsk.com
The Journal of Organic Chemistry
|May 10, 2003
Abstract:
An efficient and regioselective synthesis of 2-methyl-2H-indazoles and 2-ethyl-2H-indazoles using trimethyloxonium tetrafluoroborate or triethyloxonium hexafluorophosphate is reported.
Related Concept Videos
Articles linked to this work by shared authors, journal, and citation graph.
Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis.
The Journal of pharmacology and experimental therapeutics·2023
TACH101, a first-in-class pan-inhibitor of KDM4 histone demethylase.
Anti-cancer drugs·2023
Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf.
Journal of medicinal chemistry·2021
Discovery of Orally Bioavailable Ligand Efficient Quinazolindiones as Potent and Selective Tankyrases Inhibitors.
ACS medicinal chemistry letters·2021
Photoinduced, Pd-Catalyzed Glycosyl Three-Component Reaction: Access to C-Alkyl Glycoside via 1,4-Glycosylamination of 1,3-Butadiene.
The Journal of organic chemistry·2026
Ru-Catalyzed Transfer Hydrogenation of N-Heterocycles Using Ammonium Formate as a Hydrogen Source.
The Journal of organic chemistry·2026
Oxidative Deboronation of Organic Boron-Containing Molecules by Oxidants HOX or Oxygen: Computational Mapping of Mechanistic Alternatives.
The Journal of organic chemistry·2026
Direct Synthesis of Pyrazolones via N-B Bond Functionalization: Sequential Carbonyl Insertion Using In Situ Generated N,N'-Diborylated Hydrazines.
The Journal of organic chemistry·2026
Reaction of Thioesters and Selenoesters with Diazo Reagents: Formal Carbene Insertion into C-S and C-Se Bonds.
The Journal of organic chemistry·2026
Base-Mediated Cyclization of N-Benzyl Ketimines with Diynes: Conditions-Controlled Switching between N-Vinyl Pyrroles and 2H-Azepines.
The Journal of organic chemistry·2026
Inorganic Nanoparticles: Applications in Ophthalmology.
Biochemistry. Biokhimiia·2026
Asymmetric synthesis of fused seven-membered chromanones from 3-hydroxy chromones and vinyl ethylene carbonates.
Organic & biomolecular chemistry·2026
Iron-Photocatalyzed Alkene Chloroaminoxylation: A Platform for Orthogonally Activatable Building Blocks.
Angewandte Chemie (International ed. in English)·2026
Synthesis of Isoquinolines Through Isochromenylium Intermediates Captured by Nitriles and a CO-to-CN Switch.
Angewandte Chemie (International ed. in English)·2026