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[Course of pregnancy, delivery and newborn status in case of maternal tuberculosis]
Adolfas Pranevicius1, Vilma Radzeviciūte, Petras Bimba
1Clinics of Pulmonology and Immunology, Kaunas University of Medicine Hospital, Lithuania.
Course of pregnancy, delivery and newborns status were analyzed for 77 women with tuberculosis. The data were compared with analogical data of 72 healthy women. Almost fifty percent (49.3%) of patients were treated with antituberculous drugs in pregnancy. Eighty percent of women with tuberculosis gave birth of mature healthy newborns. Some cases of preterm rupture of membranes, preterm or postterm delivery and another complications were observed, but there was no significant difference comparing to healthy women. Anemia and congenital anomalies were significantly more common in tuberculosis group. Anemia was explained by suppressive influence on the appetite and liver function of pregnant women by specific baciliar toxicosis, antituberculous drugs and insufficient resorption of nutrition ingredients (especially iron). We are very concerned about growing number of developmental anomalies of newborns in women with tuberculosis, such as spina bifida, inherited luxation of hip joint and other abnormalities. There is a need for additional data to make a general conclusion. But it is clear that in medical institutions all women with tuberculosis must get the information how to plan pregnancy.
Course of pregnancy, delivery and newborns status were analyzed for 77 women with tuberculosis. The data were compared with analogical data of 72 healthy women. Almost fifty percent (49.3%) of patients were treated with antituberculous drugs in pregnancy. Eighty percent of women with tuberculosis gave birth of mature healthy newborns. Some cases of preterm rupture of membranes, preterm or postterm delivery and another complications were observed, but there was no significant difference comparing to healthy women. Anemia and congenital anomalies were significantly more common in tuberculosis group. Anemia was explained by suppressive influence on the appetite and liver function of pregnant women by specific baciliar toxicosis, antituberculous drugs and insufficient resorption of nutrition ingredients (especially iron). We are very concerned about growing number of developmental anomalies of newborns in women with tuberculosis, such as spina bifida, inherited luxation of hip joint and other abnormalities. There is a need for additional data to make a general conclusion. But it is clear that in medical institutions all women with tuberculosis must get the information how to plan pregnancy.
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