Reversibility of the chronic post-stroke state

Area of Science:

• Neurology
• Hyperbaric Medicine
• Neurophysiology

Background:

• Cerebral infarction due to internal carotid artery (ICA) or middle cerebral artery (MCA) occlusion presents a significant neurological challenge.
• Assessing the efficacy of novel treatments like hyperbaric oxygenation (HO) in different stroke stages is crucial.

Purpose of the Study:

• To evaluate the impact of hyperbaric oxygenation (HO) on cerebral infarction patients with ICA or MCA occlusion.
• To assess the course of cerebral lesions using electroencephalogram (EEG) analysis in early and chronic post-stroke stages.

Main Methods:

• Forty patients with cerebral infarction (ICA or MCA occlusion) were enrolled.
• Patients received hyperbaric oxygenation (HO) treatment.
• Regular electroencephalogram (EEG) analyses were conducted to monitor cerebral lesion progression.

Main Results:

• EEG analyses were performed regularly to assess the cerebral lesion's course.
• Neurological and EEG changes were distributed evenly between patients in early (Stage III B) and chronic (Stage IV) post-stroke phases.

Conclusions:

• Hyperbaric oxygenation (HO) treatment in patients with cerebral infarction associated with ICA or MCA occlusion shows observable effects on EEG and neurological status.
• The study indicates that neurological and EEG changes are comparable in both early and chronic post-stroke stages when treated with HO.