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[Urticaria and angioedema].

Mauro Cancian1, Maria Bortolati, Umberto Fagiolo

  • 1Clinica Medica I, Dipartimento di Scienze Mediche e Chirurgiche, Università degli Studi di Padova. mcancian@unipd.it

Annali Italiani Di Medicina Interna : Organo Ufficiale Della Societa Italiana Di Medicina Interna
|May 13, 2003
PubMed
Summary

Urticaria and angioedema are common skin conditions involving wheals and swelling. This review focuses on the complex diagnosis and treatment of chronic forms, particularly chronic idiopathic urticaria.

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Area of Science:

  • Dermatology
  • Immunology

Context:

  • Urticaria, characterized by itchy wheals, and angioedema, marked by deep swelling, are common conditions.
  • Mast cells play a key role in urticaria pathogenesis.
  • While acute forms often have identifiable causes, chronic urticaria and angioedema present complex diagnostic and therapeutic challenges.

Purpose:

  • To review the clinical features, diagnostic approaches, and therapeutic strategies for various forms of urticaria and angioedema.
  • To emphasize the complexities associated with chronic idiopathic urticaria.

Summary:

  • Urticaria presents as wheals with redness and itching, while angioedema involves deep dermal and subcutaneous edema.
  • Wheals are typically short-lived, unlike in urticarial vasculitis.
  • Angioedema can be life-threatening if it affects the oropharynx.

Impact:

  • Provides a comprehensive overview for clinicians managing urticaria and angioedema.
  • Highlights the need for tailored approaches to chronic and idiopathic cases.
  • Aims to improve understanding and management of these prevalent dermatological conditions.

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