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The role of the counteranion in the cation-pi interaction
Christopher A Hunter1, Caroline M R Low, Carmen Rotger
1Centre for Chemical Biology, Krebs Institute for Biomolecular Science, Department of Chemistry, University of Sheffield, Sheffield, UK S3 7HF. C.Hunter@Sheffield.ac.uk
Chemical Communications (Cambridge, England)
|May 13, 2003
Abstract:
Chemical double mutant cycles have been used to quantify cation-pi interactions in chloroform as a function of the nature of the counteranion. The cation-pi interaction is -2.5 +/- 0.4 kJ mol(-1) and independent of the anion, even though the overall stability of the complexes varies by an order of magnitude due to competition of the anion for alternative binding sites.