Donor calculi induced acute renal failure
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Updated: Sep 26, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Yasir A Qazi1, Yaqub Ali, Rocco C Venuto
1Department of Medicine, State University of New York at Buffalo School of Medicine and Biomedical Science, Erie County Medical Center, Buffalo, New York 14215, USA.
Abstract:
Nephrolithiasis is an infrequent complication following renal transplantation and acquisition of a stone with the donor kidney is rare. Indeed only a few cases of donor stones causing renal failure have been reported. Since the grafted kidney is denervated, stone disease may not present with the classic renal colic but rather with acute renal failure secondary to the obstruction. Identification of the precise cause is critical in order to avoid inappropriate therapy. We present our experience of two renal transplant patients who developed obstructive uropathy by stones originating from the donor kidneys.
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