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Updated: Aug 18, 2026
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Elevated liver enzymes as an operative complication of gastric bypass surgery
Julie Saranita1, Roy G Soto, Dan Paoli
1Resident Anesthesiology, University of South Florida College of Medicine, Department of Anesthesiology, Tampa, FL 33612, USA.
Background:
A rise in liver function tests (LFTs) had been noted in a patient following gastric bypass. This was studied in a subsequent gastric bypass patient, to determine if this rise in LFTs occurred sometime between placement of the upper abdominal retractors but before the retractors were removed.
Methods:
LFTs were drawn preoperatively, immediately before retractor placement, immediately before retractor removal, 1 and 3 hours postoperatively, and postoperatively for 5 days until discharge.
Results:
LFTs rose after liver retractor placement and remained elevated for 3 days before returning to normal.
Conclusions:
The authors postulate that surgical retractor placement may have caused the patient's acute LFT elevation. Specifically, direct mechanical pressure may result in a transient decrease in hepatic blood-flow.
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