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Cervical spine involvement in ankylosing spondylitis.

A El Maghraoui1, R Bensabbah, R Bahiri

  • 1El Ayachi Hospital, Rabat-Salé, Ibn Sina University Centre, Morocco. a_elmaghraoui@hotmail.com

Clinical Rheumatology
|May 13, 2003
PubMed
Summary

Cervical spine involvement is common in ankylosing spondylitis (AS), increasing with disease duration and severity. Early detection and management are crucial for patients, especially in North African populations.

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Area of Science:

  • Rheumatology
  • Orthopedics
  • Epidemiology

Background:

  • Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the axial skeleton.
  • Cervical spine involvement is a significant complication of AS, impacting patient mobility and quality of life.
  • Limited data exists on cervical spine involvement patterns in North African populations.

Purpose of the Study:

  • To investigate the prevalence and characteristics of cervical spine involvement in Moroccan AS patients.
  • To assess the correlation between cervical spine involvement and disease severity (symptomatic and structural).
  • To evaluate the risk of cervical spine involvement over time based on disease duration.

Main Methods:

  • Prospective enrollment of 61 ankylosing spondylitis patients over one year.

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  • Collection of clinical, biological, and radiological data.
  • Kaplan-Meier method used to estimate the risk of cervical spine involvement; statistical analyses for correlations.

    • Main Results:

    • 54% of patients exhibited radiological cervical spine involvement, with significant concordance between clinical and radiological findings.
    • Cervical spine involvement risk increased with disease duration, reaching 70% after 20 years.
    • Patients with cervical spine involvement showed significantly higher symptomatic and structural disease severity scores.

    Conclusions:

    • Cervical spine involvement is a frequent complication of ankylosing spondylitis in Moroccan patients.
    • Involvement is associated with increased disease duration and greater symptomatic and structural severity.
    • Findings suggest AS may be more severe in North African populations, highlighting the need for vigilant cervical spine monitoring.