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Updated: Sep 26, 2026

Bioassay-Guided Identification of Natural Products for Biocontrol by Thin Layer Chromatography-Direct Bioautography
Published on: July 26, 2024
[Modes of action of agrochemicals against plant pathogenic organisms]
1Unité de phytopharmacie et médiateurs chimiques, Inra, route de Saint-Cyr, 78026 Versailles, France. lerouxp@versailles.inra.fr
Abstract:
The chemical control of plant pathogens concerns mainly fungal diseases of crops. Most of the available fungicides act directly on essential fungal functions such as respiration, sterol biosynthesis or cell division. Consequently, these compounds can exhibit undesirable toxicological and environmental effects and sometimes select fungal resistant strains. Plant activators are expected to provide sustainable disease management in several crops because the development of resistance is not expected. Considering the future, the discovery of novel antifungal molecules will reap advantage from throughput screening methodologies and functional genomics.
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