Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hearing01:31

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sources of Error in Toric Intraocular Lens Power Calculation.

Journal of refractive surgery (Thorofare, N.J. : 1995)·2020
Same author

Prediction of the true IOL position.

The British journal of ophthalmology·2017
Same author

Using continuous intraoperative optical coherence tomography measurements of the aphakic eye for intraocular lens power calculation.

The British journal of ophthalmology·2014
Same author

Reply: To PMID 22709831.

American journal of ophthalmology·2012
Same author

Fluctuations in corneal curvature limit predictability of intraocular lens power calculations.

Journal of cataract and refractive surgery·2012
Same author

The final frontier: pediatric intraocular lens power.

American journal of ophthalmology·2012

Related Experiment Video

Updated: May 25, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
09:44

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Published on: January 26, 2016

Hydrogels for an accommodating intraocular lens. An explorative study.

Jacqueline H de Groot1, Coenraad J Spaans, Ralph V van Calck

  • 1Pharmacia Groningen BV, Van Swietenlaan 5, 9728 NX Groningen, The Netherlands.

Biomacromolecules
|May 14, 2003
PubMed
Summary

Novel hydrogels show promise for accommodating intraocular lenses. Researchers developed new polymers and preparation methods to achieve the necessary transparency, strength, refractive index, and low modulus for advanced lens materials.

More Related Videos

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
06:04

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages

Published on: March 24, 2023

An Automated System for Sound Localization Testing in Hearing-Impaired Listeners
07:52

An Automated System for Sound Localization Testing in Hearing-Impaired Listeners

Published on: March 13, 2026

Related Experiment Videos

Last Updated: May 25, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
09:44

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Published on: January 26, 2016

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
06:04

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages

Published on: March 24, 2023

An Automated System for Sound Localization Testing in Hearing-Impaired Listeners
07:52

An Automated System for Sound Localization Testing in Hearing-Impaired Listeners

Published on: March 13, 2026

Area of Science:

  • Biomaterials Science
  • Ophthalmic Materials Engineering

Background:

  • Conventional hydrogels lack the required properties for accommodating intraocular lenses.
  • Developing materials with a low modulus, high refractive index, transparency, and strength is crucial for advanced lens technology.

Purpose of the Study:

  • To investigate the potential of novel hydrogels as materials for accommodating intraocular lenses.
  • To develop and characterize new hydrogel formulations with specific optical and mechanical properties.

Main Methods:

  • Synthesized and cross-linked various polymers including poly(1-hydroxy-1,3-propanediyl), poly(ethylene-co-vinyl alcohol), poly(vinyl alcohol), and poly(allyl alcohol).
  • Utilized controlled network formation in dilute solutions with specific diisocyanate cross-linkers.
  • Employed compression molding for poly(allyl alcohol) hydrogel preparation.
  • Evaluated key properties such as refractive index, transparency, tensile strength, and modulus.

Main Results:

  • Poly(1-hydroxy-1,3-propanediyl) hydrogel, cross-linked with a slow-reacting diisocyanate, exhibited optimal refractive index, transparency, tensile strength, and modulus.
  • Poly(allyl alcohol) hydrogel demonstrated transparency, a high refractive index, and a low modulus.
  • Careful control over polymer solution and cross-linker mixing was critical for achieving transparency.

Conclusions:

  • Hydrogels can be engineered to meet the demanding requirements of accommodating intraocular lenses.
  • The developed poly(1-hydroxy-1,3-propanediyl) and poly(allyl alcohol) hydrogels represent promising candidates for next-generation ophthalmic lens materials.