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Updated: Aug 10, 2026

Isolation of Murine Lymph Node Stromal Cells
Published on: August 19, 2014
Social stress affects migration of blood T cells into lymphoid organs
Volker Stefanski1, André Peschel, Stefan Reber
1Department of Animal Physiology, University of Bayreuth, 95440 Bayreuth, Germany. volker.stefanski@uni-bayreuth.de
Abstract:
The effect of social confrontation stress on the normal distribution of blood T cells into lymphoid organs and some other body tissues was studied. Social stress was induced by placing a male Fischer 344 (F334) rat into the home cage of a resident opponent. 51Cr-labeled blood T cells isolated from syngeneic donor, were intravenously injected into recipients immediately before confrontation. The accumulation of 51Cr-labeled T cells in the spleen, mesenteric and cervical lymph nodes 24 h after injection was about 30% lower in socially stressed than in control males. Substantially higher localization was observed in the bone marrow of socially stressed males.
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