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Multiple Epstein-Barr virus infections in healthy individuals
Dennis M Walling1, Abigail L Brown, Wiguins Etienne
1Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch at Galveston 77555, USA. dwalling@utmb.edu
Journal of Virology
|May 14, 2003
Abstract:
We employed a newly developed genotyping technique with direct representational detection of LMP-1 gene sequences to study the molecular epidemiology of Epstein-Barr virus (EBV) infection in healthy individuals. Infections with up to five different EBV genotypes were found in two of nine individuals studied. These results support the hypothesis that multiple EBV infections of healthy individuals are common. The implications for the development of an EBV vaccine are discussed.